It is handled the same way; a ggplotly object is a plotly object.
p <- ggplot(data = d, aes(x = carat, y = price)) +
geom_point(aes(text = paste("Clarity:", clarity)), size = 4) +
geom_smooth(aes(colour = cut, fill = cut))
ggplotly(p) %>% config(displayModeBar = F) %>% layout(xaxis=list(fixedrange=TRUE)) %>% layout(yaxis=list(fixedrange=TRUE))
